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M9490051.TXT
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1994-09-03
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Document 0051
DOCN M9490051
TI [Immunological findings of bronchoalveolar lavage fluid (BALF) in
sarcoidosis; analysis of soluble CD4 molecule and soluble CD8 molecule]
DT 9411
AU Sato S; Second Department of Internal Medicine, Nagoya City University;
Medical School.
SO Nippon Rinsho. 1994 Jun;52(6):1550-5. Unique Identifier : AIDSLINE
MED/94322483
AB Since the introduction of bronchoalveolar lavage (BAL) by Reynolds and
Newball in 1974, this procedure has been used to characterize the
cellular and soluble components of alveolar lining fluid in many
interstitial lung diseases. We reviewed BAL fluid findings of clinical
and pathophysiologic researches in patients with pulmonary sarcoidosis.
Moreover, our recent data about soluble CD4 molecule (sCD4) and soluble
CD8 molecule (sCD8) were also described. The sarcoidosis patients had
the significantly higher level of sCD4 in BAL fluid compared with normal
subjects. The level of sCD8 in serum in active sarcoidosis was
significantly higher than that in normal subjects. Furthermore,
significant correlation between the levels of serum sCD8 and ACE was
observed in sarcoidosis.
DE Adult Antigens, CD4/*ANALYSIS Antigens, CD8/*ANALYSIS Bronchoalveolar
Lavage Fluid/*IMMUNOLOGY CD4-CD8 Ratio English Abstract Female Human
Male Prognosis Sarcoidosis, Pulmonary/*IMMUNOLOGY Smoking Solubility
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).